Amphotericin B is a polyene antifungal drug. Fungi sensitive to this product include Cryptococcus neoformans, Blastomyces dermatitis, histoplasm, coccidium, Sporothrix, Candida, etc. Some Aspergillus are resistant to this product; Dermatophytes and Trichophyton are mostly drug-resistant. This product has no antimicrobial activity against bacteria, Rickettsia, viruses, etc. The drug concentration reached by the commonly used therapeutic dose has only antibacterial effect on fungi.
The advantages of amphotericin B are as follows:
Amphotericin B is effective against almost most fungi, with few drug-resistant strains and low price, so it still shows high practical value in clinical application for more than 40 years. This means that people benefit greatly from amphotericin B.
The main clinical indications are as follows:
① Treatment of cryptococcosis, North American blastomycosis, disseminated candidiasis, coccidioidomycosis, and histoplasmosis.
② Treatment of mucormycosis caused by rhizopus, unfavorable fungus, endophyte and faecal mold.
③ Treatment of sporotrichosis caused by Sporotrichum schenckii.
④ treatment of aspergillosis caused by Aspergillus fumigatus.
⑤External preparations are suitable for pigmented mycoses, skin fungal infections after burns, respiratory Candida, Aspergillus or cryptococcal infections, and fungal corneal ulcers.
Amphotericin B Suppliers - Minbiotch
Shanghai Minbiotch Co., Ltd. is a company specializing in the research, development and production of advanced pharmaceutical intermediates and biological raw materials. Committed to providing a variety of high-end generic drugs and innovative drugs. Production and sales of amphotericin B, welcome to visit our website or contact us.
Amphotericin B related products
